JOSÉ MANUEL FERNÁNDEZ-REAL LEMOS

Projectes

Nutrition, Eumetabolism and Health

Stratification of Obese Phenotypes to Optimize Future Obesity Therapy

Codi oficial: SOPHIA Start date:09/07/2020 Data fi: 08/07/2025 Investigador/a principal: JOSÉ MANUEL FERNÁNDEZ-REAL LEMOS Organisme finançador: EUROPEAN COMISSION Ajuda: 300,000 €

Nutrition, Eumetabolism and Health

Ayuda de personal PFIS

Codi oficial: FI19/00293 Start date:01/01/2020 Data fi: 31/12/2023 Investigador/a principal: JOSÉ MANUEL FERNÁNDEZ-REAL LEMOS Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 82,400 €

Nutrition, Eumetabolism and Health

Ayuda de personal Sara Borrell

Codi oficial: CD20/00051 Start date:01/01/2021 Data fi: 17/06/2024 Investigador/a principal: JOSÉ MANUEL FERNÁNDEZ-REAL LEMOS Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 80,598 €

Nutrition, Eumetabolism and Health

Gut-brain-axis: Targets for improvement of cognition in the elderly

Codi oficial: SMARTAGE Start date:01/09/2020 Data fi: 31/08/2024 Investigador/a principal: JORDI MAYNERIS PERXACHS, JOSÉ MANUEL FERNÁNDEZ-REAL LEMOS Organisme finançador: EUROPEAN COMISSION Ajuda: 417,569.76 €

Nutrition, Eumetabolism and Health

Evaluating Microbiome Causality in the Gut-Liver Axis and Impact on Insulin Resistance

Codi oficial: 19/0006059 Start date:03/02/2020 Data fi: 02/02/2024 Investigador/a principal: JOSÉ MANUEL FERNÁNDEZ-REAL LEMOS Organisme finançador: DIABETES UK Ajuda: 0 €

Nutrition, Eumetabolism and Health

SUCCINATE/SUCNR1 AXIS: A NOVEL TARGET FOR ANTI-OBESITY THERAPIES

Codi oficial: METASUCC Start date:01/12/2020 Data fi: 31/12/2024 Investigador/a principal: JOSÉ MANUEL FERNÁNDEZ-REAL LEMOS Organisme finançador: FUND. BANCARIA "LA CAIXA" Ajuda: 258,752.50 €

Nutrition, Eumetabolism and Health

Ajuda de personal PERIS Lisset de la Vega

Codi oficial: SLT017/20/000164 Start date:12/07/2021 Data fi: 31/12/2024 Investigador/a principal: JOSÉ MANUEL FERNÁNDEZ-REAL LEMOS Organisme finançador: GENERALITAT DE CATALUNYA Ajuda: 92,623.53 €

Nutrition, Eumetabolism and Health

Interrelaciones entre las reservas de hierro, el metagenoma intestinal, los niveles de glucosa y diferentes dominios cognitivos: el papel de los microARN circulantes

Codi oficial: PI21/01361 Start date:01/01/2022 Data fi: 31/12/2024 Investigador/a principal: JOSÉ MANUEL FERNÁNDEZ-REAL LEMOS Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 304,920 €

Nutrition, Eumetabolism and Health

Dianas terapéuticas y biomarcadores de la medicina de precisión en MAFLD.

Codi oficial: PMP21/00072 Start date:01/01/2022 Data fi: 31/12/2025 Investigador/a principal: JORDI MAYNERIS PERXACHS, JOSÉ MANUEL FERNÁNDEZ-REAL LEMOS Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 141,185 €

Nutrition, Eumetabolism and Health

Involvement of the gut microbiota-brain cross talk in the loss of eating control

Codi oficial: HR22-00737 Start date:01/10/2022 Data fi: 30/09/2025 Investigador/a principal: JOSÉ MANUEL FERNÁNDEZ-REAL LEMOS Organisme finançador: FUND. BANCARIA "LA CAIXA" Ajuda: 374,894.76 €

Nutrition, Eumetabolism and Health

Ayuda de personal Intensificación 2022

Codi oficial: INT22/00015 Start date:01/01/2023 Data fi: 31/12/2024 Investigador/a principal: JOSÉ MANUEL FERNÁNDEZ-REAL LEMOS Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 60,000 €

Nutrition, Eumetabolism and Health

Ajuts per donar suport a les activitats dels grups de recerca de Catalunya (SGR-Cat 2021) - Nutrició, Eumetabolisme i Salut

Codi oficial: 2021 SGR 01263 Start date:01/01/2022 Data fi: 31/12/2024 Investigador/a principal: JOSÉ MANUEL FERNÁNDEZ-REAL LEMOS Organisme finançador: AGENCIA DE GESTIO D'AJUTS UNIV. I RECER. Ajuda: 60,000 €

Nutrition, Eumetabolism and Health

Nuevos retos en investigación sobre plasticidad adiposa (ADIPOBROAD)

Codi oficial: RED2022-134313-T Start date:01/06/2023 Data fi: 31/05/2025 Investigador/a principal: JOSÉ MANUEL FERNÁNDEZ-REAL LEMOS Organisme finançador: MINISTERIO DE ECONOMIA Y COMPETITIVIDAD MINECO / Ajuda: 0 €

Nutrition, Eumetabolism and Health

Ajuda de personal Suport als grups PERIS - Grup de Recerca Nutrició Eumetabolisme i Salut

Codi oficial: SLT028/23/000133 Start date:01/08/2023 Data fi: 31/12/2025 Investigador/a principal: JOSÉ MANUEL FERNÁNDEZ-REAL LEMOS Organisme finançador: GENERALITAT DE CATALUNYA Ajuda: 75,784.93 €

Publicacions

Nutrition, Eumetabolism and Health

Milbank E, Díaz-Trelles R, Dragano N, Latorre J, Mukthavaram R, Mayneris-Perxachs J, Ortega F, Federici M, Burcelin R, Karmali PP, Tachikawa K, Chivukula P, López M, Fernández-Real JM, Moreno-Navarrete JM

Liver lipopolysaccharide binding protein prevents hepatic inflammation in physiological and pathological non-obesogenic conditions

PHARMACOLOGICAL RESEARCH, 2023, 187, 106562-106562 dx.doi.org/10.1016/j.phrs.2022.106562

Nutrition, Eumetabolism and Health

Champion C, Neagoe RM, Effernberger M, Sala DT, Servant F, Christensen JE, Arnoriaga-Rodriguez M, Amar J, Lelouvier B, Loubieres P, Azalbert V, Minty M, Thomas C, Blasco-Baque V, Gamboa F, Tilg H, Cardellini M, Federici M, Fernández-Real JM, Loubes JM, Burcelin R

Human liver microbiota modeling strategy at the early onset of fibrosis.

BMC MICROBIOLOGY, 2023, 23, 34-34 dx.doi.org/10.1186/s12866-023-02774-4

Medical Imaging , Nutrition, Eumetabolism and Health

Hinojosa-Moscoso A, Motger-Albertí A, De la Calle-Vargas E, Martí-Navas M, Biarnés C, Arnoriaga-Rodríguez M, Blasco G, Puig J, Luque-Córdoba D, Priego-Capote F, Moreno-Navarrete JM, Fernández-Real JM

The Longitudinal Changes in Subcutaneous Abdominal Tissue and Visceral Adipose Tissue Volumetries Are Associated with Iron Status.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 dx.doi.org/10.3390/ijms24054750

Nutrition, Eumetabolism and Health

González-Moro I, Rojas-Márquez H, Sebastian-delaCruz M, Mentxaka-Salgado J, Olazagoitia-Garmendia A, Mendoza LM, Lluch A, Fantuzzi F, Lambert C, Ares Blanco J, Marselli L, Marchetti P, Cnop M, Delgado E, Fernández-Real JM, Ortega FJ, Castellanos-Rubio A, Santin I

A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells.

Frontiers in Endocrinology, 2023, 14, 1101934-1101934 dx.doi.org/10.3389/fendo.2023.1101934

Nutrition, Eumetabolism and Health

Valenti L, Corradini E, Adams LA, Aigner E, Alqahtani S, Arrese M, Bardou-Jacquet E, Bugianesi E, Fernandez-Real JM, Girelli D, Hagström H, Henninger B, Kowdley K, Ligabue G, McClain D, Lainé F, Miyanishi K, Muckenthaler MU, Pagani A, Pedrotti P, Pietrangelo A, Prati D, Ryan JD, Silvestri L, Spearman CW, Stål P, Tsochatzis EA, Vinchi F, Zheng MH, Zoller H

Consensus Statement on the definition and classification of metabolic hyperferritinaemia.

NATURE REVIEWS ENDOCRINOLOGY, 2023, 19, 1-12 dx.doi.org/10.1038/s41574-023-00807-6

Medical Imaging , Cerebrovascular Pathology , Private: Aging, Disability and Health , Neurodegeneration and Neuroinflammation , Nutrition, Eumetabolism and Health , Cardiovascular Genetics , Research in Vascular Health

Sol J, Obis È, Mota-Martorell N, Pradas I, Galo-Licona JD, Martin-Garí M, Fernández-Bernal A, Ortega-Bravo M, Mayneris-Perxachs J, Borrás C, Viña J, de la Fuente M, Mate I, Biarnes C, Pedraza S, Vilanova JC, Brugada R, Ramos R, Serena J, Ramió-Torrentà L, Pineda V, Daunis-I-Estadella P, Thió-Henestrosa S, Barretina J, Garre-Olmo J, Portero-Otin M, Fernández-Real JM, Puig J, Jové M, Pamplona R

Plasma acylcarnitines and gut-derived aromatic amino acids as sex-specific hub metabolites of the human aging metabolome.

Aging Cell, 2023, 22 dx.doi.org/10.1111/acel.13821

Nutrition, Eumetabolism and Health

Mayneris-Perxachs J, Fernández-Real JM

Proline-related metabolites: Towards biological diagnosis of depression.

PSYCHIATRY AND CLINICAL NEUROSCIENCES, 2023, 77, 195-195 dx.doi.org/10.1111/pcn.13535

Nutrition, Eumetabolism and Health

Villanueva-Carmona T, Cedó L, Madeira A, Ceperuelo-Mallafré V, Rodríguez-Peña MM, Núñez-Roa C, Maymó-Masip E, Repollés-de-Dalmau M, Badia J, Keiran N, Mirasierra M, Pimenta-Lopes C, Sabadell-Basallote J, Bosch R, Caubet L, Escolà-Gil JC, Fernández-Real JM, Vilarrasa N, Ventura F, Vallejo M, Vendrell J, Fernández-Veledo S

SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression.

CELL METABOLISM, 2023, 35 dx.doi.org/10.1016/j.cmet.2023.03.004

Nutrition, Eumetabolism and Health

Arnoriaga-Rodríguez M, Leal Y, Mayneris-Perxachs J, Pérez-Brocal V, Moya A, Ricart W, Fernández-Balsells M, Fernández-Real JM

Gut microbiota composition and functionality are associated with REM sleep duration and continuous glucose levels.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2023, 108, 2931-2939 dx.doi.org/10.1210/clinem/dgad258

Nutrition, Eumetabolism and Health

Amin A, Badenes M, Tüshaus J, de Carvalho É, Burbridge E, Faísca P, Trávnícková K, Barros A, Carobbio S, Domingos PM, Vidal-Puig A, Moita LF, Maguire S, Stríšovský K, Ortega FJ, Fernández-Real JM, Lichtenthaler SF, Adrain C

Semaphorin 4B is an ADAM17-cleaved adipokine that inhibits adipocyte differentiation and thermogenesis.

Molecular Metabolism, 2023, 73, 101731-101731 dx.doi.org/10.1016/j.molmet.2023.101731

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Propietat intel·lectual

José Manuel Fernández-real Lemos

METHOD FOR DIAGNOSING HEPATIC FIBROSIS

Número de publicació: WO2015162200 Data de publicació: 2015-10-29

José Manuel Fernández-real Lemos

METHOD FOR DIAGNOSING HEPATIC FIBROSIS BASED ON BACTERIAL PROFILE AND DIVERSITY

Número de publicació: WO2017060039 Data de publicació: 2018-08-15

José Manuel Fernández-real Lemos

METHODS FOR DETERMINING WHETHER A SUBJECT HAS OR IS AT RISK OF HAVING A NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) OR ONE OF ITS COMPLICATIONS

Número de publicació: WO2019077125 Data de publicació: 2019-04-25

Directori

Projectes

Publicacions

Liver lipopolysaccharide binding protein prevents hepatic inflammation in physiological and pathological non-obesogenic conditions

Human liver microbiota modeling strategy at the early onset of fibrosis.

The Longitudinal Changes in Subcutaneous Abdominal Tissue and Visceral Adipose Tissue Volumetries Are Associated with Iron Status.

A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells.

Consensus Statement on the definition and classification of metabolic hyperferritinaemia.

Plasma acylcarnitines and gut-derived aromatic amino acids as sex-specific hub metabolites of the human aging metabolome.

Proline-related metabolites: Towards biological diagnosis of depression.

SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression.

Gut microbiota composition and functionality are associated with REM sleep duration and continuous glucose levels.

Semaphorin 4B is an ADAM17-cleaved adipokine that inhibits adipocyte differentiation and thermogenesis.

Propietat intel·lectual

METHOD FOR DIAGNOSING HEPATIC FIBROSIS

METHOD FOR DIAGNOSING HEPATIC FIBROSIS BASED ON BACTERIAL PROFILE AND DIVERSITY

METHODS FOR DETERMINING WHETHER A SUBJECT HAS OR IS AT RISK OF HAVING A NON-ALCOHOLIC FATTY LIVER DISEASE (NAFLD) OR ONE OF ITS COMPLICATIONS

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