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The Infections, sepsis and multi-organ dysfunction in the patient group was initially created as a group of professionals from the intensive care medicine department of the Hospital Josep Trueta with the aim of understanding the pathogenesis of infections and sepsis in the critically ill patient. Subsequently it has become more complex and now includes the critical patient as a whole, sepsis and multi-organ dysfunction, all within an intensive care environment that aims to be more humanised (H-ICU).

The scope of action is in the ICU of the Hospital Doctor Josep Trueta in Girona and the ICU of the Hospital Santa Caterina in Salt, which share intensive care professionals from the same service.

Main lines of research
  • Research in infections and antibiotic treatment of critically ill patients
  • Research on sepsis and septic shock
  • Research in microbiota of the critically ill patient
  • Research in critical patient nutrition
  • Research in sedation, analgesia and delirium
  • Research in neurocritical patient
  • Research in fluids and extracorporeal clearance techniques
  • Research in ventilation and oxygenation techniques
  • Research in humanisation of the critical patient and post-ICU syndrome
  • Research and clinical trials at COVID-19
Strategic objectives

After 10 years with a strategic line basically of studies on infectious diseases of the critical patient and phase III clinical trials of new antibiotics, in recent years everything has become more complex and broader and now the strategic lines are more varied but we want to group them in the same research group.

Thus the grouping of different lines and projects helps to increase the power and strength of the group of studies of the critical patient.


Is serum hyperosmolality related with myocardial dysfunction in septic shock patients?


Individuals With SARS-CoV-2 Infection During the First and Second Waves in Catalonia, Spain: Retrospective Observational Study Using Daily Updated Data

JMIR Public Health and Surveillance, 2022, 8

Vidal-Cortés P, Díaz Santos E, Aguilar Alonso E, Amezaga Menéndez R, Ballesteros MÁ, Bodí MA, Bordejé Laguna ML, Garnacho Montero J, García Sánchez M, López Sánchez M, Martín-Loeches I, Ochagavía Calvo A, Ramírez Galleymore P, Alcántara Carmona S, Andaluz Ojeda D, Badallo Arébalo O, Barrasa González H, Borges Sa M, Castellanos-Ortega Á, Estella Á, Ferrer Roca R, Fraile Gutiérrez V, Fuset Cabanes M, Giménez-Esparza Vich C, González Iglesias C, Hernández-Tejedor A, Igeño Cano JC, Iglesias Posadilla D, Jiménez Rivera JJ, Llanos Jorge C, Llompart-Pou JA, López Camps V, Lorencio Cárdenas C, Marcos Neira P, Martín Delgado MC, Martín-Macho González M, Martín Villén L, Nuvials Casals X, Ortiz Suñer A, Quintana Díaz M, Rascado Sedes P, Recuerda Núñez M, Del Río Carbajo L, Rodríguez Aguirregabiria M, Rodríguez Oviedo A, Seijas Betolaza I, Soriano Cuesta C, Suberviola Cañas B, Vera Ching C, Vidal González Á, Zapata Fenor L, Zaragoza Crespo R

Recommendations for the management of critically ill patients with COVID-19 in Intensive Care Units.

Medicina Intensiva, 2022, 46, 81-89

Wendel-Garcia PD, Mas A, González-Isern C, Ferrer R, Máñez R, Masclans JR, Sandoval E, Vera P, Trenado J, Fernández R, Sirvent JM, Martínez M, Ibarz M, Garro P, Lopera JL, Bodí M, Yébenes-Reyes JC, Triginer C, Vallverdú I, Baró A, Bodí F, Saludes P, Valencia M, Roche-Campo F, Huerta A, Cambra FJ, Barberà C, Echevarria J, Peñuelas Ó, Mancebo J, UCIsCAT study group

Non-invasive oxygenation support in acutely hypoxemic COVID-19 patients admitted to the ICU: a multicenter observational retrospective study

CRITICAL CARE, 2022, 26, 37-37

Sirvent JM, Baro A, Morales M, Sebastian P, Saiz X

Predictive biomarkers of mortality in critically ill patients with COVID-19.

Medicina Intensiva, 2022, 46, 94-96

Trends in mortality in septic patients according to the different organ failure during 15 years

CRITICAL CARE, 2022, 26, 302-302

Dysbiosis: An Indicator of COVID-19 Severity in Critically Ill Patients.


Enteral nutrition in critically ill patients under vasoactive drug therapy: The NUTRIVAD study.


The Effect of Enteral Immunonutrition in the Intensive Care Unit: Does It Impact on Outcomes?

Nutrients, 2022, 14

Evaluation of Nutritional Practices in the Critical Care patient (The ENPIC study): Does nutrition really affect ICU mortality?

Clinical Nutrition ESPEN, 2022, 47, 325-332
Competitive projects
Clinical guidelines
Ballesteros MÁ,Hernández A,Estella Á,Jiménez JJ,González de Molina Ortiz FJ,Sandiumenge A,Vidal P,de Haro C,Aguilar E,Bordejé L,García I,Bodí M,García M,Párraga MJ,Alcaraz RM,Amézaga R,Burgueño P,Grupos de Trabajo de la Sociedad Española de Medicina Intensiva CYU,Grupos de Trabajo de la Sociedad Española de Medicina Intensiva CYU,Grupo de Trabajo de Cuidados Intensivos Cardiológicos YRCP,Grupo de Trabajo de Cuidados Intensivos N,Grupo de Trabajo de Donación Trasplantes Y,Grupo de Trabajo de Enfermedades Infecciosas Sepsis Y,Grupo de Trabajo de Evaluación de Tecnologías Metodología de la Investigación Y,Grupo de Trabajo de Insuficiencia Respiratoria A,Grupo de Trabajo de Metabolismo Nutrición Y,Grupo de Trabajo de Neurointensivismo Trauma Y,Grupo de Trabajo de Planificación OYG,Grupo de Trabajo de Sedación AYD,Grupo de Trabajo de S,Grupo de Trabajo de T,Grupo de Trabajo de Transfusiones Hemoderivados Y,Grupo de Trabajo de Transporte C,Junta D,Rubio O,Rodríguez MÁ,Fraile V,Fuset MP,Zapata L,Montesinos de la Peña MG,Ortega A,Navas A,Arias MD,Pont T,Maraví E,Rubio JJ,Del Río F,Catalán M,Díaz E,Iglesias D,Riera M,Vera C,Lorencio C,González C,Riveiro M,Enríquez P,Igeño JC,Cruz M,Trenado J,Riera M,Carlos J,Sánchez M,Giménez C,Priego J,Broch MJ,de la Fuente MV,Martín MC,Palacios D,Fernández A,Socias A,Baldirà J,Gero M,Quintana M,Marcos P,Serrano A,Argudo E,Ferrer R,Castellanos Á,Trenado J,Fraile V,Herrera M,Ramírez P,Rascado P,de la Oliva LL,Martín MC. Recommendations of the Working Groups from the Spanish Society of Intensive and  Critical Care Medicine and Coronary Units (SEMICYUC) for the management of adult  critically ill patients in the coronavirus disease (COVID-19). MED INTENSIVA. 2020. 44(6):p. 371-388. IF:2,491. PMID: 32360034.
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