Respiratory

The Respiratory Research Group at IDIBGI includes several researchers from the Pulmonology Service. It is focused on research into bronchiectasis, sleep disorders, occupational respiratory diseases, and interstitial lung diseases.

The research is complemented by intense clinical activity, which has led the group to be invited to conferences in international congresses, to carrying out draft reviews and to publishing in high impact journals, as well as to being experts in the field of respiratory diseases, both nationally and internationally.

Main lines of research

Bronchiectasis: Etiology, diagnosis, and treatment
Sleep disorders: Diagnosis in primary medicine and vascular repercussions of the disease
Pulmonary hypertension
Early diagnosis of lung cancer
Occupational respiratory pathologies
Diffuse interstitial lung disease

Strategic objectives

Bronchiectasis: objectives: to investigate in the field of Bronchiectasis with different aetiologies, including cystic fibrosis, in terms of etiology, diagnosis, bronchial infection, and treatment.
Obstructive sleep Apnoea Syndrome (OSA): Objectives: Early diagnosis, endothelial and metabolic dysfunction and identification of plasma and cellular biomarkers.
Chronic Thromboembolic Pulmonary Hypertension (CTEPH): Objectives: New therapeutic targets, causes of the disease, vascular dysfunctions and in vitro 3D and in vivo models of endothelial pathology within CTEPH.
Lung cancer: Objectives: Detection of ctDNA as a diagnostic tool in lung cancer.
COVID-19: Objectives: Advanced respiratory therapies in COVID-19 patients. Pulmonary respiratory and vascular sequelae in patients that have been through COVID-19.

Publications

Infections, sepsis and multi-organ dysfunction in the patient , Internal Medicine , Respiratory

Persons with SARS-CoV-2 during the First and Second Waves in Catalonia (Spain): A Retrospective Observational Study Using Daily Updated Data.

JMIR Public Health and Surveillance, 2022, 8 dx.doi.org/10.2196/30006

Respiratory , Internal Medicine

Post-COVID-19 patients show an increased endothelial progenitor cell production.

Translational Research : The Journal Of Laboratory And Clinical Medicine, 2022, 243, 14-20 dx.doi.org/10.1016/j.trsl.2022.01.004

Internal Medicine , Respiratory

Evolving mortality and clinical outcomes of hospitalized subjects during successive COVID-19 waves in Catalonia, Spain.

Global Epidemiology, 2022, 4, 100071-100071 dx.doi.org/10.1016/j.gloepi.2022.100071

Respiratory

Isolated lobar consolidation as a form of presentation of pulmonary MALT lymphoma.

MEDICINA CLINICA, 2022, 158, 298-298 dx.doi.org/10.1016/j.medcli.2021.06.005

Respiratory

Endothelial Dysfunction and Cardiovascular Risk in Obstructive Sleep Apnea: A Review Article.

LIFE-BASEL, 2022, 12 dx.doi.org/10.3390/life12040537

Respiratory

Challenges for asthma units in response to COVID-19: a qualitative group dynamics analysis.

JOURNAL OF ASTHMA, 2022, 59, 1-8 dx.doi.org/10.1080/02770903.2021.1917605

Respiratory Respiratory Respiratory

Higher mortality and intubation rate in COVID-19 patients treated with noninvasive ventilation compared with high-flow oxygen or CPAP.

SCIENTIFIC REPORTS, 2022, 12, 6527-6527 dx.doi.org/10.1038/s41598-022-10475-7

Respiratory

Differences and Similarities between the Lung Transcriptomic Profiles of COVID-19, COPD, and IPF Patients: A Meta-Analysis Study of Pathophysiological Signaling Pathways.

LIFE-BASEL, 2022, 12 dx.doi.org/10.3390/life12060887

Respiratory

Metabolic profile in endothelial cells of chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension.

SCIENTIFIC REPORTS, 2022, 12, 2283-2283 dx.doi.org/10.1038/s41598-022-06238-z

Respiratory

The Interplay between Pathophysiological Pathways in Early-Onset Severe Preeclampsia Unveiled by Metabolomics.

LIFE-BASEL, 2022, 12 dx.doi.org/10.3390/life12010086

12 3 4 5 6

Competitive projects

Respiratory

Benefits of inhalation of 7% hypertonic saline solution prior to ELTGOL physiotherapy, in patients with bronchiectasis. A randomized controlled trial

Codi oficial: FISHT2021 Start date:15/12/2021 Data fi: 31/12/2026 Investigador/a principal: MONTSERRAT VENDRELL RELAT Organisme finançador: SOC. ESP. NEUMOLOGIA Y CIRURGIA TORACICA Ajuda: 11,160 €

Respiratory

Impacte de la COVID-19 en pacients amb bronquièctasis no degudes a fibrosi quística.

Codi oficial: COVBQ-21 Start date:18/08/2021 Data fi: 18/08/2023 Investigador/a principal: MONTSERRAT VENDRELL RELAT Organisme finançador: COL·LEGI FISIOTERAPEUTES DE CATALUNYA Ajuda: 0 €

Respiratory

Disfunció endotelial, metobolòmica i biomarcadors en pacients amb la sindrome d'apnea obstructiva del son (SAOS) lleu i moderat.

Codi oficial: DISON Start date:28/12/2021 Data fi: 31/12/2022 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: SOC. ESP. NEUMOLOGIA Y CIRURGIA TORACICA Ajuda: 2,045.61 €

Respiratory

La detecció de ctDNA com a eina de diagnòstic en la neoplàsia de pulmó.

Codi oficial: ctDNA Start date:08/03/2022 Data fi: 31/12/2022 Investigador/a principal: RAMON ORRIOLS MARTINEZ Organisme finançador: SOC. ESP. NEUMOLOGIA Y CIRURGIA TORACICA Ajuda: 11,400 €

Respiratory

Estudio del orígen y caracteristicas de la disfunción endotelial en la HPTEC y en la COVID-19 (SIENA).

Codi oficial: PI21/01212 Start date:01/01/2022 Data fi: 31/12/2024 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 129,470 €

Respiratory

ESTUDIO DEL METABOLISMO Y DE LA FUNCIÓN ENDOTELIAL EN PACIENTES CON HIPERTENSIÓN PULMONAR TROMBOEMBÓLICA: EFECTO DE LA ESTIMULACIÓN DE RIOCIGUAT.

Codi oficial: PI18/00960 Start date:01/01/2019 Data fi: 30/06/2023 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 159,115 €

Respiratory

Diagnostic and treatment of Sleep Apnea Hypopnea Syndrome in Primary Care

Codi oficial: 210450 Start date:01/01/2022 Data fi: 31/12/2024 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: EUROPEAN INSTITUTE OF TECHNOLOGY Ajuda: 130,956 €

Respiratory

Network For Research In Vascular Ageing

Codi oficial: CA18216 Start date:05/11/2019 Data fi: 04/11/2023 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: EUROPEAN COOPERATION IN SCIENCE AND TECHNOLOGY (COST) Ajuda: 0 €

Respiratory

Ajuda de personal FI - Sana Ayyoub

Codi oficial: 2022 FI_B 00941 Start date:01/06/2022 Data fi: 31/05/2025 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: AGENCIA DE GESTIO D'AJUTS UNIV. I RECER. Ajuda: 69,143.51 €

Respiratory

Estudio del metabolismo y de la función endotelial en pacientes con hipertensión pulmonar tromboembólica: efecto de la estimulación de Riociguat.

Codi oficial: 907/2019 Start date:28/12/2021 Data fi: 31/12/2022 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: SOC. ESP. NEUMOLOGIA Y CIRURGIA TORACICA Ajuda: 13,950 €

Respiratory

Disfunción endotelial en pacientes tras superar la COVID-19: secuelas y complicaciones cardiopulmonares.

Codi oficial: 1087 Start date:28/12/2021 Data fi: 31/12/2022 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: SOC. ESP. NEUMOLOGIA Y CIRURGIA TORACICA Ajuda: 5,580 €

Transfer

Guies clíniques

- Martínez-García MÁ, Máiz L, Olveira C, Girón RM, de la Rosa D, Blanco M, Cantón R, Vendrell M, Polverino E, de Gracia J, Prados C. Spanish Guidelines on the Evaluation and Diagnosis of Bronchiectasis in Adults. Arch Bronconeumol. 2018 Feb;54(2):79-87. doi: 10.1016/j.arbres.2017.07.015. Epub 2017 Nov 9. English, Spanish.

- Polverino E, Goeminne PC, McDonnell MJ, Aliberti S, Marshall SE, Loebinger MR, Murris M, Cantón R, Torres A, Dimakou K, De Soyza A,, Hill AT, Haworth CS, Vendrell M, Ringshausen FC19, Subotic D20, Wilson R, Vilaró J, Stallberg B, Welte T, Rohde G, Blasi F, Elborn S, Almagro M, Timothy A, Ruddy T, Tonia T, Rigau D, Chalmers JD. European Respiratory Society guidelines for the management of adult bronchiectasis. European Respiratory Journal. 2017 Sep 9;50(3)

Job offers

Persons with SARS-CoV-2 during the First and Second Waves in Catalonia (Spain): A Retrospective Observational Study Using Daily Updated Data.

Post-COVID-19 patients show an increased endothelial progenitor cell production.

Evolving mortality and clinical outcomes of hospitalized subjects during successive COVID-19 waves in Catalonia, Spain.

Isolated lobar consolidation as a form of presentation of pulmonary MALT lymphoma.

Endothelial Dysfunction and Cardiovascular Risk in Obstructive Sleep Apnea: A Review Article.

Challenges for asthma units in response to COVID-19: a qualitative group dynamics analysis.

Higher mortality and intubation rate in COVID-19 patients treated with noninvasive ventilation compared with high-flow oxygen or CPAP.

Differences and Similarities between the Lung Transcriptomic Profiles of COVID-19, COPD, and IPF Patients: A Meta-Analysis Study of Pathophysiological Signaling Pathways.

Metabolic profile in endothelial cells of chronic thromboembolic pulmonary hypertension and pulmonary arterial hypertension.

The Interplay between Pathophysiological Pathways in Early-Onset Severe Preeclampsia Unveiled by Metabolomics.

Guies clíniques

Team

Group leader - R4

Established researchers - R3

Postdoctorals researchers – R2

Predoctorals researchers – R1

Collaborators

Non-scientific research support staff

Research technicians

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