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Main lines of research

-Intersection between sleep diseases, cardiovascular risk, senescence and ageing.
-Development of early diagnosis methods for lung cancer.
-Study of the links between COVID-19, cardiovascular risk and COVID persistence.
-Research on respiratory diseases and intestinal dysbiosis with special attention to the lung-gut axis.
-Analysis of pulmonary hypertension, pulmonary embolism and endothelial dysfunction.
-Identification of biomarkers in cardiopulmonary diseases.
-Implementation of 2D and 3D vascular models, organ-on-a-chip and animal models to deepen the understanding of the underlying mechanisms.

Strategic objectives

Sleep Disorders and Cardiovascular Risk, Senescence and Ageing:

-Investigate the molecular relationships between sleep diseases and the development of cardiovascular problems.

-Identify possible treatments to mitigate the effects of poor sleep on the senescence process.

Early diagnosis of lung cancer:

- Develop new early detection technologies with the aim of improving survival rates in lung cancer patients.

COVID-19, Cardiovascular Risk and Persistent COVID:

-Investigate the mechanisms linking COVID-19 infection with cardiovascular risk. Compare with other respiratory viruses

Understand the persistence of COVID and its long-term effects on cardiovascular health.

Respiratory Diseases and Intestinal Dysbiosis (Lung-Gut Axis):

-Exploring the molecular interactions between the respiratory system and the gut microbiota to better understand dysbiosis and its impact on respiratory diseases.

Pulmonary Hypertension, Pulmonary Embolism and Endothelial Dysfunction:

-Investigate the pathophysiological mechanisms of pulmonary hypertension and pulmonary embolism.

-To develop therapeutic strategies aimed at improving the associated endothelial dysfunction.

Study of Biomarkers in Cardiopulmonary Diseases:

-Identify and validate specific biomarkers for different cardiopulmonary diseases.

-Establish standardised protocols for the clinical use of the identified biomarkers.

2D and 3D Vascular Models, Organ-on-a-Chip and Animal Models:

-Optimise and validate in vitro vascular models for preclinical studies.

-To integrate the different models to obtain a more complete view of the physiopathological processes in cardiopulmonary diseases.

Publications
Ayyoub S, Dhillon NK, Tura-Ceide O

Genetics of Long COVID: Exploring the Molecular Drivers of Persistent Pulmonary Vascular Disease Symptoms.

Infectious Disease Reports, 2025, 17 dx.doi.org/10.3390/idr17010015
POYATOS DORADO, PAULA, GRATACÓS AURICH, MIQUEL, AYYOUB, SANA, TURA CEIDE, OLGA

Chapter 18 - Vascular manifestations of COVID-19: Endothelial dysfunction and damage

Understanding the Pandemic: Pathophysiology, Transmission and Treatment of COVID-19, 2025, 323-334 dx.doi.org/https://doi.org/10.1016/B978-0-443-19170-1.00034-6
Blanco, I, Casós, K, Gómez-Hernández, I, Armora, AB, Sardiné, A, Tura-Ceide, O, Fernández-Hernández, R, Barbera, JA, Peinado, VI

Effects of Physical Training on Mitochondrial Dynamic in Pulmonary Arterial Hypertension

American journal of respiratory and critical care medicine, 2025, 211
Blanco, I, Aguilar, D, Casós, K, Gómez-Hernández, I, Tura-Ceide, O, Serrano-Mollar, A, Barbera, JA, Peinado, VI

Effects of Low-intensity Exercise on Pulmonary Arterial Hypertension: A Comprehensive Transcriptomic Analysis of Lung, Heart and Muscle

American journal of respiratory and critical care medicine, 2025, 211
Sardiné, A, Fernández-Hernández, R, Colindres, RA, Valle, YR, Armora, AB, Ramirez, A, Rosado, A, Benguría, A, Dopazo, A, Peinado, VI, Blanco, I, Tura-Ceide, O, Barbera, JA

Functional Characterization of Pulmonary Endothelial Cells Harvested From Pulmonary Artery Catheter in Pulmonary Arterial Hypertension: Effect of Treatment

American journal of respiratory and critical care medicine, 2025, 211
Poyatos P, Luque N, Sabater G, Eizaguirre S, Bonnin M, Orriols R, Tura-Ceide O

Endothelial dysfunction and cardiovascular risk in post-COVID-19 patients after 6-and 12-months SARS-CoV-2 infection

Infection, 2024, 52, 1269-1285 dx.doi.org/10.1007/s15010-024-02173-5
Peracaula, M, Martinez-Blanco, A, Gavara, N, Gratacos, M, Peinado, V, Blanco,, Barbera, JA, Tura-Ceide, O

Endothelial cells in chronic thromboembolic pulmonary hypertension exhibit cytoskeletal alteration

CARDIOVASCULAR RESEARCH, 2024, 120 dx.doi.org/10.1093/cvr/cvae088.184
de la Bastida-casero, L, García-León, B, Tura-Ceide, O, Oliver, E

The Relevance of the Endothelium in Cardiopulmonary Disorders

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 dx.doi.org/10.3390/ijms25179260
Peracaula, M, Sebastian, L, Francisco, I, Vilaplana, MB, Rodríguez-Chiaradía, DA, Tura-Ceide, O

Decoding Pulmonary Embolism: Pathophysiology, Diagnosis, and Treatment

Biomedicines, 2024, 12 dx.doi.org/10.3390/biomedicines12091936
Peracaula, M, Rodríguez, C, Ramírez, AM, Osorio, J, Rigol, M, Blanco, I, Peinado, V, Castellà, M, Barberà, JA, Turaceide, O

Comparative analysis of circulating endothelial progenitor cells and resected tissue- derived endothelial cells in chronic thromboembolic pulmonary hypertension (CTEPH)

EUROPEAN RESPIRATORY JOURNAL, 2024, 64 dx.doi.org/10.1183/13993003.congress-2024.PA5230
Competitive projects
Codi oficial: PI21/01212- SIENA Start date:01/01/2022 Data fi: 30/06/2026 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: INSTITUTO DE SALUD CARLOS III
Codi oficial: 1087 Start date:28/12/2021 Data fi: 31/12/2025 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: SOCIEDAD ESPAÑOLA NEUMOLOGIA Y CIRUGIA TORACICA (SEPAR)
Codi oficial: CPII22/00006 Start date:01/06/2023 Data fi: 31/05/2026 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: INSTITUTO DE SALUD CARLOS III
Codi oficial: FI22/00133 Miriam Peracaula Start date:01/01/2023 Data fi: 31/12/2026 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: INSTITUTO DE SALUD CARLOS III
Codi oficial: 202336-30 Start date:22/04/2024 Data fi: 21/04/2027 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: FUNDACIO LA MARATO TV3
Codi oficial: 2023_SEC_OTC Start date:16/06/2023 Data fi: 31/12/2027 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: SOCIEDAD ESPAÑOLA DE CARDIOLOGIA
Codi oficial: CNS2023-145362 Start date:01/04/2024 Data fi: 30/06/2026 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: MINISTERIO DE ECONOMIA E INNOVACION
Codi oficial: GLD24/00100 Start date:01/01/2025 Data fi: 01/12/2026 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: GILEAD SCIENCES, S.L.U
Codi oficial: 2024_ACM_OTC Start date:01/03/2023 Data fi: 01/03/2026 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: FUNDACIÓ ACADÈMIA CIÈNCIES MÈDIQUES
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