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Main lines of research

-Intersection between sleep diseases, cardiovascular risk, senescence and ageing.
-Development of early diagnosis methods for lung cancer.
-Study of the links between COVID-19, cardiovascular risk and COVID persistence.
-Research on respiratory diseases and intestinal dysbiosis with special attention to the lung-gut axis.
-Analysis of pulmonary hypertension, pulmonary embolism and endothelial dysfunction.
-Identification of biomarkers in cardiopulmonary diseases.
-Implementation of 2D and 3D vascular models, organ-on-a-chip and animal models to deepen the understanding of the underlying mechanisms.

Strategic objectives

Sleep Disorders and Cardiovascular Risk, Senescence and Ageing:

-Investigate the molecular relationships between sleep diseases and the development of cardiovascular problems.

-Identify possible treatments to mitigate the effects of poor sleep on the senescence process.

Early diagnosis of lung cancer:

- Develop new early detection technologies with the aim of improving survival rates in lung cancer patients.

COVID-19, Cardiovascular Risk and Persistent COVID:

-Investigate the mechanisms linking COVID-19 infection with cardiovascular risk. Compare with other respiratory viruses

Understand the persistence of COVID and its long-term effects on cardiovascular health.

Respiratory Diseases and Intestinal Dysbiosis (Lung-Gut Axis):

-Exploring the molecular interactions between the respiratory system and the gut microbiota to better understand dysbiosis and its impact on respiratory diseases.

Pulmonary Hypertension, Pulmonary Embolism and Endothelial Dysfunction:

-Investigate the pathophysiological mechanisms of pulmonary hypertension and pulmonary embolism.

-To develop therapeutic strategies aimed at improving the associated endothelial dysfunction.

Study of Biomarkers in Cardiopulmonary Diseases:

-Identify and validate specific biomarkers for different cardiopulmonary diseases.

-Establish standardised protocols for the clinical use of the identified biomarkers.

2D and 3D Vascular Models, Organ-on-a-Chip and Animal Models:

-Optimise and validate in vitro vascular models for preclinical studies.

-To integrate the different models to obtain a more complete view of the physiopathological processes in cardiopulmonary diseases.

Publications
Ayyoub S, Dhillon NK, Tura-Ceide O

Genetics of Long COVID: Exploring the Molecular Drivers of Persistent Pulmonary Vascular Disease Symptoms.

Infectious Disease Reports, 2025, 17 dx.doi.org/10.3390/idr17010015
Poyatos P, Luque N, Sabater G, Eizaguirre S, Bonnin M, Orriols R, Tura-Ceide O

Endothelial dysfunction and cardiovascular risk in post-COVID-19 patients after 6-and 12-months SARS-CoV-2 infection

Infection, 2024, 52, 1269-1285 dx.doi.org/10.1007/s15010-024-02173-5
Peracaula, M, Martinez-Blanco, A, Gavara, N, Gratacos, M, Peinado, V, Blanco,, Barbera, JA, Tura-Ceide, O

Endothelial cells in chronic thromboembolic pulmonary hypertension exhibit cytoskeletal alteration

CARDIOVASCULAR RESEARCH, 2024, 120 dx.doi.org/10.1093/cvr/cvae088.184
de la Bastida-casero, L, García-León, B, Tura-Ceide, O, Oliver, E

The Relevance of the Endothelium in Cardiopulmonary Disorders

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2024, 25 dx.doi.org/10.3390/ijms25179260
Peracaula, M, Sebastian, L, Francisco, I, Vilaplana, MB, Rodríguez-Chiaradía, DA, Tura-Ceide, O

Decoding Pulmonary Embolism: Pathophysiology, Diagnosis, and Treatment

Biomedicines, 2024, 12 dx.doi.org/10.3390/biomedicines12091936
Peracaula, M, Rodríguez, C, Ramírez, AM, Osorio, J, Rigol, M, Blanco, I, Peinado, V, Castellà, M, Barberà, JA, Turaceide, O

Comparative analysis of circulating endothelial progenitor cells and resected tissue- derived endothelial cells in chronic thromboembolic pulmonary hypertension (CTEPH)

EUROPEAN RESPIRATORY JOURNAL, 2024, 64 dx.doi.org/10.1183/13993003.congress-2024.PA5230
Oliveira SD, Almodóvar S, Butrous G, De Jesus Perez V, Fabro A, Graham BB, Mocumbi A, Nyasulu PS, Tura-Ceide O, Oliveira RKF, Dhillon NK

Infection and pulmonary vascular diseases consortium: United against a global health challenge.

Pulmonary Circulation, 2024, 14 dx.doi.org/10.1002/pul2.70003
Callejo, M, Morales-Cano, D, Olivencia, MA, Mondejar-Parreño, G, Barreira, B, Tura-Ceide, O, Martínez, VG, Serrano-Navarro, A, Moreno, L, Morrell, N, Perros, F, Vicente, A, Cogolludo, A, Perez-Vizcaino, F

Vitamin D receptor and its antiproliferative effect in human pulmonary arterial hypertension

SCIENTIFIC REPORTS, 2024, 14, 27445-27445 dx.doi.org/10.1038/s41598-024-78380-9
Blanco, I, Casós, K, Gomez, I, Tura-Ceide, O, Barbera, JA, Peinado, V

Effects of Physical Training on Mitochondrial Function in Pulmonary Arterial Hypertension

American journal of respiratory and critical care medicine, 2024, 209
Armora, AB, Garcia, AR, Lozano, J, Sidorova, J, Blanco, I, Martín, C, Tura-Ceide, O, Peinado, VI, Rodriguez, D, López-Meseguer, M, Hernandez-Gonzalez, F, Ribas, J, Pomares, X, Santos, S, Molina-Molina, M, Torres, JS, Barbera, JA

Different Proteomic Profiles in Severe Pulmonary Hypertension Associated With COPD and Pulmonary Fibrosis

American journal of respiratory and critical care medicine, 2024, 209
Competitive projects
Codi oficial: PI21/01212- SIENA Start date:01/01/2022 Data fi: 30/06/2026 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: INSTITUTO DE SALUD CARLOS III
Codi oficial: 2022 FI_B 00941 Start date:01/06/2022 Data fi: 31/05/2025 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: AGÈNCIA DE GESTIÓ UNIVERSITARIS I RECERCA
Codi oficial: CPII22/00006 Start date:01/06/2023 Data fi: 31/05/2026 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: INSTITUTO DE SALUD CARLOS III
Codi oficial: FI22/00133 Miriam Peracaula Start date:01/01/2023 Data fi: 31/12/2026 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: INSTITUTO DE SALUD CARLOS III
Codi oficial: 202336-30 Start date:22/04/2024 Data fi: 21/04/2027 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: FUNDACIO LA MARATO TV3
Codi oficial: 2023_SEC_OTC Start date:16/06/2023 Data fi: 31/12/2027 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: SOCIEDAD ESPAÑOLA DE CARDIOLOGIA
Codi oficial: CNS2023-145362 Start date:01/04/2024 Data fi: 30/06/2026 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: MINISTERIO DE ECONOMIA E INNOVACION
Codi oficial: GLD24/00100 Start date:01/01/2025 Data fi: 01/12/2026 Investigador/a principal: OLGA TURA CEIDE Organisme finançador: GILEAD SCIENCES, S.L.U
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