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Internal Medicine is the main medical discipline in the care of adults with one or several complex acute or chronic diseases. The main areas of action are the complex chronic patient, acute patient, medical and surgical unit support, management of multi-organ diseases and the diagnosis and management of poorly defined syndromic pictures and minority diseases. Our Internal Medicine Service manages 1300 annual discharges, 1100 hospital interconsultations and 800 first visits to outpatient clinics. The main DRGs are infectious diseases, cardiac insufficiency and venous thromboembolic disease, as well as systemic-autoimmune diseases due to their idiosyncrasy.

From this environment arises the type of research in which the group feels involved, basically clinical-epidemiological to better understand the risk factors, diagnosis, treatment and prognosis of the pathologies that we assist.

Currently the staff is made up of 14 doctors with a post and 7 resident doctors. Most of them are interested and involved in research.

Main lines of research
  • Venous thromboembolic disease
  • Infectious Diseases: COVID-19, AIDS, MTS, Tuberculosis, ARI/Pneumonia.
  • Cardiac insufficiency
  • Autoimmune-systemic diseases.
Strategic objectives
  • Clinical-epidemiological research
  • Participation in National Registries
  • Participation in Phase II-III Clinical Trials
  • Development of Doctoral Theses
Publications
Barca-Hernando M, Otalora-Valderrama S, Lopez-Nuñez JJ, Portillo-Sanchez J, Pagan-Escribano J, Lopez-Miguel P, Mahe I, Mena-Muñoz E, Jou-Segovia I, Imbalzano E, Agudo-de Blas P, Lorenzo-Hernandez A, Diaz-Pedroche C, Aibar-Gallizo J, de la Red-Bellvis G, Del Molino-Sanz F, Amado-Fernandez C, Fernandez-Reyes JL, Villalobos-Sanchez A, Lopez-Saez JB, Diaz-Brasero AM, Marcos-Jubilar M, Meireles J, Marchena-Yglesias PJ, Diaz-Peromingo JA, Marin-Romero S, Elias-Hernandez T, Andrade-Ruiz HA, Mehdipour G, Bikdeli B, Jara-Palomares L

Occult cancer in patients with unprovoked venous thromboembolism: Rationale, design, and methods of the VaLRIETEs study and the SOME-RIETE trial.

AMERICAN HEART JOURNAL, 2025, 284, 81-93 dx.doi.org/10.1016/j.ahj.2025.02.004
Marin-Romero S, Ballaz-Quincoces A, Gómez-Cuervo C, Marchena-Yglesias PJ, Lopez-Miguel P, Francisco-Albesa I, Pedrajas-Navas JM, Lumbierres M, Aibar-Arregui MA, Bosco Lopez-Saez J, Perez-Pinar M, Baeza-Martinez C, Riera-Mestre A, Peris-Sifre M, Porras-Ledantes JA, Criado-Garcia J, Elias-Hernandez T, Otero R, Barca-Hernando M, Muriel A, Klok FA, Jara-Palomares L

Symptom-related screening programme for early detection of chronic thromboembolic pulmonary hypertension after acute pulmonary embolism: the SYSPPE study

Thorax, 2024, 79, 144-152 dx.doi.org/10.1136/thorax-2023-220580
Brito-Zerón P, Flores-Chávez A, González-de-Paz L, Feijoo-Massó C, de Escalante B, González-García A, Gómez-de-la-Torre R, Policarpo-Torres G, Alguacil A, García-Morillo JS, López-Dupla M, Robles Á, Bonet M, Gómez-Lozano A, Toledo N, Chamorro A, Morcillo C, Cruz-Caparrós G, de Miguel-Campo B, Akasbi M, Fonseca-Aizpuru E, Gómez-Cerezo JF, Mas-Maresma L, Vallejo-Grijalba J, Starita-Fajardo G, Sánchez-Niño R, Ramos-Casals M

Temporal relationship between sarcoidosis and malignancies in a nationwide cohort of 1942 patients.

POSTGRADUATE MEDICAL JOURNAL, 2024, 100, 898-907 dx.doi.org/10.1093/postmj/qgae045
Trullàs JC, Moreno-García MC, Mittelbrunn-Alquézar V, Conde-Martel A, Soler-Rangel L, Montero-Pérez-Barquero M, Casado J, Sánchez-Marteles M, Arévalo-Lorido JC, Pérez-Silvestre J

The RICA-2 registry: Design and baseline characteristics of the first 1,000 patients.

Revista Clinica Espanola, 2024, 224, 522-533 dx.doi.org/10.1016/j.rceng.2024.07.008
Ruiz Hueso R, Salamanca Bautista P, Quesada Simón MA, Yun S, Conde Martel A, Morales Rull JL, Fiteni Mera I, Abad Pérez D, Páez Rubio I, Aramburu Bodas Ó

Cardiac amyloidosis worsens prognosis in patients with heart failure: Findings from the PREVAMIC study.

Revista Clinica Espanola, 2024, 224, 494-502 dx.doi.org/10.1016/j.rceng.2024.07.006
Peracaula, M, Sebastian, L, Francisco, I, Vilaplana, MB, Rodríguez-Chiaradía, DA, Tura-Ceide, O

Decoding Pulmonary Embolism: Pathophysiology, Diagnosis, and Treatment

Biomedicines, 2024, 12 dx.doi.org/10.3390/biomedicines12091936
López Fernández MJ, Narejos S, Castro A, Echave-Sustaeta JM, Forner MJ, Arana-Arri E, Molto J, Bernad L, Pérez-Caballero R, Prado JG, Raïch-Regué D, Boreika R, Izquierdo-Useros N, Trinité B, Blanco J, Puig-Barberà J, Natalini Martínez S

Omicron XBB.1.16-Adapted Vaccine for COVID-19: Interim Immunogenicity and Safety Clinical Trial Results.

Vaccines, 2024, 12 dx.doi.org/10.3390/vaccines12080840
Larrea Urtaran X, Dordà Benito A, Gratacós Santanach L, Nogué Pujadas E, Aguilar Salmeron R, Salgado Serrano X

Patient with allergy to first-line anti-tuberculosis drugs

REVISTA ESPANOLA DE QUIMIOTERAPIA, 2024, 37, 196-198 dx.doi.org/10.37201/req/140.2023
Branford JA, Bodaghi B, Ferreira LB, McCluskey PJ, Thorne JE, Matthews JM, Smith JR

Use of immunomodulatory treatment for non-infectious uveitis: an International Ocular Inflammation Society report of real-world practice.

BRITISH JOURNAL OF OPHTHALMOLOGY, 2024 dx.doi.org/10.1136/bjo-2024-326239
Negre Busó M, Alvarez Martínez G, Rubió Rodríguez A

Utility of 18F-FDG PET/CT in the diagnosis and follow-up of a patient with eosinophilic granulomatosis with polyangiitis and large vessel vasculitis.

MEDICINA CLINICA, 2024, 163, 524-525 dx.doi.org/10.1016/j.medcli.2024.05.010
Competitive projects
Codi oficial: 101046118 Start date:01/12/2021 Data fi: 31/08/2025 Investigador/a principal: RAFEL RAMOS BLANES, RAMON BRUGADA TERRADELLAS, ANTONI CASTRO GUARDIOLA Organisme finançador: EUROPEAN COMISSION
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