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Projectes

Investigación Metabólica y Maternofetal

Genomic imprinting in postnatal growth and impact thereon of parental obesity

Codi oficial: PI19/00451 Data inicio:01/01/2020 Data fi: 31/12/2023 Investigador/a principal: JUDIT BASSOLS CASADEVALL, ABEL LÓPEZ BERMEJO Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 101,640 €
Investigación Metabólica y Maternofetal

Análisis longitudinal de las marcas de metilación del DNA asociadas con la obesidad infantil

Codi oficial: PI20/00399 Data inicio:01/01/2021 Data fi: 31/12/2024 Investigador/a principal: JUDIT BASSOLS CASADEVALL Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 93,170 €
Investigación Metabólica y Maternofetal

PCOS in Adolescent Girls and Young Women: Toward a Treatment Guided by Pathophysiology

Codi oficial: 210653186 Data inicio:01/04/2021 Data fi: 31/03/2026 Investigador/a principal: JUDIT BASSOLS CASADEVALL, ABEL LÓPEZ BERMEJO Organisme finançador: EUROPEAN COMISSION Ajuda: 231,535 €
Obesidad y riesgo cardiovascular en pediatría

A Phase II, randomised, multi-centric, multi-national clinical trial to evaluate the efficacy, tolerability, and safety of a fixed dose combination of Spironolactone, Pioglitazone & Metformin (SPIOMET) for adolescent girls and young adult women (AYAs) with polycystic ovary syndrome (PCOS)

Codi oficial: ICI21/00005 Data inicio:01/01/2022 Data fi: 31/12/2025 Investigador/a principal: ABEL LÓPEZ BERMEJO Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 193,256.37 €
Obesidad y riesgo cardiovascular en pediatría

Epigenética en niñas con pubertad adelantada y predicción de su evolución puberal

Codi oficial: PI22/00366 Data inicio:01/01/2023 Data fi: 31/12/2025 Investigador/a principal: ABEL LÓPEZ BERMEJO Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 93,170 €
Obesidad y riesgo cardiovascular en pediatría

Efectos del tratamiento con Spiomet a mitad de dosis en niñas con pubertad adelantada y aceleración de la maduración ósea: Estudio multicéntrico, aleatorizado y controlado con placebo

Codi oficial: ICI21/00005 Data inicio:01/01/2022 Data fi: 31/12/2025 Investigador/a principal: JUDIT BASSOLS CASADEVALL, ABEL LÓPEZ BERMEJO Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 193,256.37 €

Publicacions

Marzuillo P, Carreras-Badosa G, Martínez-Calcerrada JM, Guarino S, Palma PL, Petrone D, Miraglia Del Giudice E, Bassols J, López-Bermejo A

Body surface area-based kidney length percentiles misdiagnose small kidneys in children with overweight/obesity

PEDIATRIC NEPHROLOGY, 2023, 38, 1523-1532 dx.doi.org/10.1007/s00467-022-05718-8
Díaz M, Carreras-Badosa G, Villarroya J, Gavaldà-Navarro A, Bassols J, de Zegher F, López-Bermejo A, Villarroya F, Ibáñez L

Circulating GDF15 concentrations in girls with low birth weight: effects of prolonged metformin treatment

PEDIATRIC RESEARCH, 2023, 93, 964-968 dx.doi.org/10.1038/s41390-022-02175-9
Bassols J, de Zegher F, Diaz M, Carreras-Badosa G, Garcia-Beltran C, Puerto-Carranza E, Oliver-Vila C, Casano P, Franco CA, Malpique R, López-Bermejo A, Ibáñez L

Effects of half-dose spiomet treatment in girls with early puberty and accelerated bone maturation: a multicenter, randomized, placebo-controlled study protocol.

Trials, 2023, 24, 56-56 dx.doi.org/10.1186/s13063-022-07050-w
Carreras-Badosa G, Puerto-Carranza E, Mas-Parés B, Gómez-Vilarrubla A, Cebrià-Fondevila H, Díaz-Roldán F, Riera-Pérez E, de Zegher F, Ibañez L, Bassols J, López-Bermejo A

Circulating free T3 associates longitudinally with cardio-metabolic risk factors in euthyroid children with higher TSH.

Frontiers in Endocrinology, 2023, 14, 1172720-1172720 dx.doi.org/10.3389/fendo.2023.1172720
Suárez-Ortegón MF, Prats-Puig A, Bassols J, Carreras-Badosa G, McLachlan S, Wild SH, López-Bermejo A, Fernández-Real JM

Iron status and cardiometabolic risk in children.

DIABETES RES CLIN PR, 2023, 202, 110795-110795 dx.doi.org/10.1016/j.diabres.2023.110795
Gómez-Vilarrubla A, Mas-Parés B, Carreras-Badosa G, Xargay-Torrent S, Prats-Puig A, Bonmatí-Santané A, de Zegher F, Ibañez L, López-Bermejo A, Bassols J

Placental epigenetic marks related to gestational weight gain reveal potential genes associated with offspring obesity parameters.

Obesity, 2023, 31, 1903-1912 dx.doi.org/10.1002/oby.23780
Gómez-Vilarrubla A, Mas-Parés B, Carreras-Badosa G, Jové M, Berdún R, Bonmatí-Santané A, de Zegher F, Ibañez L, López-Bermejo A, Bassols J

Placental AA/EPA Ratio Is Associated with Obesity Risk Parameters in the Offspring at 6 Years of Age.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 dx.doi.org/10.3390/ijms241210087
Carreras-Badosa G, Remesar X, Prats-Puig A, Xargay-Torrent S, Lizarraga-Mollinedo E, de Zegher F, Ibáñez L, Bassols J, López-Bermejo A

Correction: Dlk1 expression relates to visceral fat expansion and insulin resistance in male and female rats with postnatal catch-up growth.

PEDIATRIC RESEARCH, 2023 dx.doi.org/10.1038/s41390-023-02691-2
Mas-Parés B, Xargay-Torrent S, Gómez-Vilarrubla A, Carreras-Badosa G, Prats-Puig A, De Zegher F, Ibáñez L, Bassols J, López-Bermejo A

Gestational Weight Gain Relates to DNA Methylation in Umbilical Cord, Which, In Turn, Associates with Offspring Obesity-Related Parameters.

Nutrients, 2023, 15 dx.doi.org/10.3390/nu15143175
Carreras-Badosa G, Puerto-Carranza E, Mas-Parés B, Gómez-Vilarrubla A, Gómez-Herrera B, Díaz-Roldán F, Riera-Pérez E, de Zegher F, Ibañez L, Bassols J, López-Bermejo A

Higher levels of serum a-Klotho are longitudinally associated with less central obesity in girls experiencing weight gain.

Frontiers in Endocrinology, 2023, 14, 1218949-1218949 dx.doi.org/10.3389/fendo.2023.1218949

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