RNA interference-mediated silencing of the p53 tumor-suppressor protein drastically increases apoptosis after inhibition of endogenous fatty acid metabolism in breast cancer cells.
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, 2005, 15, 33-40
The estrogenic activity of synthetic progestins used in oral contraceptives enhances fatty acid synthase-dependent breast cancer cell proliferation and survival.
INTERNATIONAL JOURNAL OF ONCOLOGY, 2005, 26, 1507-1515
Fatty acid synthase-catalyzed de novo fatty acid biosynthesis: from anabolic-energy-storage pathway in normal tissues to jack-of-all-trades in cancer cells.
ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS, 2004, 52, 414-426
Pharmacological inhibition of fatty acid synthase (FAS): a novel therapeutic approach for breast cancer chemoprevention through its ability to suppress Her-2/neu (erbB-2) oncogene-induced malignant transformation.
López-Pousa S, Garre-Olmo J, Turon-Estrada A, Hernández F, Expósito I, Lozano-Gallego M, Hernández-Ferrándiz M, Gelada-Batlle E, Pericot-Nierga I, Vilalta-Franch J
Análisis de los costes de la enfermedad de Alzheimer en función del deterioro cognitivo y funcional.
Inhibition of tumor-associated fatty acid synthase activity enhances vinorelbine (Navelbine)-induced cytotoxicity and apoptotic cell death in human breast cancer cells.
Hong K, Brugada J, Oliva A, Berruezo-Sanchez A, Potenza D, Pollevick GD, Guerchicoff A, Matsuo K, Burashnikov E, Dumaine R, Towbin JA, Nesterenko V, Brugada P, Antzelevitch C, Brugada R
Value of electrocardiographic parameters and ajmaline test in the diagnosis of Brugada syndrome caused by SCN5A mutations.