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FRANCISCO JOSÉ ORTEGA DELGADO

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FRANCISCO JOSÉ ORTEGA-DELGADO
Posició
Investigador/a Consolidat - R3
Investigador/a Consolidat - R3
curriculum

Projectes

Codi oficial: MS19/00109 Data inici: 01/01/2020 Data fi: 31/12/2024 Investigador/a principal: FRANCISCO JOSÉ ORTEGA DELGADO Organisme finançador: INSTITUTO DE SALUD CARLOS III
Codi oficial: PI21/00074 Data inici: 01/01/2022 Data fi: 31/12/2024 Investigador/a principal: FRANCISCO JOSÉ ORTEGA DELGADO Organisme finançador: INSTITUTO DE SALUD CARLOS III
Codi oficial: 2021 SGR 01263 Data inici: 01/01/2022 Data fi: 30/06/2025 Investigador/a principal: JOSÉ MANUEL FERNÁNDEZ-REAL LEMOS Organisme finançador: AGENCIA DE GESTIO D'AJUTS UNIV. I RECER.
Codi oficial: SLT028/23/000133 Data inici: 01/08/2023 Data fi: 31/12/2025 Investigador/a principal: JOSÉ MANUEL FERNÁNDEZ-REAL LEMOS Organisme finançador: GENERALITAT DE CATALUNYA

Publicacions

Milbank E, Díaz-Trelles R, Dragano N, Latorre J, Mukthavaram R, Mayneris-Perxachs J, Ortega F, Federici M, Burcelin R, Karmali PP, Tachikawa K, Chivukula P, López M, Fernández-Real JM, Moreno-Navarrete JM

Liver lipopolysaccharide binding protein prevents hepatic inflammation in physiological and pathological non-obesogenic conditions

PHARMACOLOGICAL RESEARCH, 2023, 187, 106562-106562 dx.doi.org/10.1016/j.phrs.2022.106562
González-Moro I, Rojas-Márquez H, Sebastian-delaCruz M, Mentxaka-Salgado J, Olazagoitia-Garmendia A, Mendoza LM, Lluch A, Fantuzzi F, Lambert C, Ares Blanco J, Marselli L, Marchetti P, Cnop M, Delgado E, Fernández-Real JM, Ortega FJ, Castellanos-Rubio A, Santin I

A long non-coding RNA that harbors a SNP associated with type 2 diabetes regulates the expression of TGM2 gene in pancreatic beta cells.

Frontiers in Endocrinology, 2023, 14, 1101934-1101934 dx.doi.org/10.3389/fendo.2023.1101934
Amin A, Badenes M, Tüshaus J, de Carvalho É, Burbridge E, Faísca P, Trávnícková K, Barros A, Carobbio S, Domingos PM, Vidal-Puig A, Moita LF, Maguire S, Stríšovský K, Ortega FJ, Fernández-Real JM, Lichtenthaler SF, Adrain C

Semaphorin 4B is an ADAM17-cleaved adipokine that inhibits adipocyte differentiation and thermogenesis.

Molecular Metabolism, 2023, 73, 101731-101731 dx.doi.org/10.1016/j.molmet.2023.101731
Lluch A, Latorre J, Serena-Maione A, Espadas I, Caballano-Infantes E, Moreno-Navarrete JM, Oliveras-Cañellas N, Ricart W, Malagón MM, Martin-Montalvo A, Birchmeier W, Szymanski W, Graumann J, Gómez-Serrano M, Sommariva E, Fernández-Real JM, Ortega FJ

Impaired Plakophilin-2 in obesity breaks cell cycle dynamics to breed adipocyte senescence.

NATURE COMMUNICATIONS, 2023, 14, 5106-5106 dx.doi.org/10.1038/s41467-023-40596-0
Oliveras-Cañellas N, Latorre J, Santos-González E, Lluch A, Ortega F, Mayneris-Perxachs J, Fernández-Real JM, Moreno-Navarrete JM

Inflammatory response to bacterial lipopolysaccharide drives iron accumulation in human adipocytes.

BIOMEDICINE & PHARMACOTHERAPY, 2023, 166, 115428-115428 dx.doi.org/10.1016/j.biopha.2023.115428
Rodríguez-Barrueco R, Latorre J, Devis-Jáuregui L, Lluch A, Bonifaci N, Llobet FJ, Olivan M, Coll-Iglesias L, Gassner K, Davis ML, Moreno-Navarrete JM, Castells-Nobau A, Plata-Peña L, Dalmau-Pastor M, Höring M, Liebisch G, Olkkonen VM, Arnoriaga-Rodríguez M, Ricart W, Fernández-Real JM, Silva JM, Ortega FJ, Llobet-Navas D

A microRNA Cluster Controls Fat Cell Differentiation and Adipose Tissue Expansion By Regulating SNCG

Advanced Science, 2022, 9 dx.doi.org/10.1002/advs.202104759
Latorre J, Ortega F, Oliveras-Cañellas N, Comas F, Lluch A, Gavaldà-Navarro A, Morón-Ros S, Ricart W, Villarroya F, Giralt M, Fernández-Real JM, Moreno-Navarrete JM

Specific adipose tissue Lbp gene knockdown prevents diet-induced body weight gain, impacting fat accretion-related gene and protein expression

MOLECULAR THERAPY-NUCLEIC ACIDS, 2022, 27, 870-879 dx.doi.org/10.1016/j.omtn.2022.01.002
Comas F, Díaz-Trelles R, Gavaldà-Navarro A, Milbank E, Dragano N, Morón-Ros S, Mukthavaram R, Latorre J, Ortega F, Arnoriaga-Rodriguez M, Oliveras-Cañellas N, Ricart W, Karmali PP, Tachikawa K, Chivukula P, Villarroya F, Giralt M, López M, Fernández-Real JM, Moreno-Navarrete JM

Downregulation of peripheral lipopolysaccharide binding protein impacts on perigonadal adipose tissue only in female mice

BIOMEDICINE & PHARMACOTHERAPY, 2022, 151, 113156-113156 dx.doi.org/10.1016/j.biopha.2022.113156
Latorre J, Díaz-Trelles R, Comas F, Gavaldà-Navarro A, Milbank E, Dragano N, Morón-Ros S, Mukthavaram R, Ortega F, Castells-Nobau A, Oliveras-Cañellas N, Ricart W, Karmali PP, Tachikawa K, Chivukula P, Villarroya F, López M, Giralt M, Fernández-Real JM, Moreno-Navarrete JM

Downregulation of hepatic lipopolysaccharide binding protein improves lipogenesis-induced liver lipid accumulation

MOLECULAR THERAPY-NUCLEIC ACIDS, 2022, 29, 599-613 dx.doi.org/10.1016/j.omtn.2022.08.003
Martínez C, Latorre J, Ortega F, Arnoriaga-Rodríguez M, Lluch A, Oliveras-Cañellas N, Díaz-Sáez F, Aragonés J, Camps M, Gumà A, Ricart W, Fernández-Real JM, Moreno-Navarrete JM

Serum neuregulin 4 is negatively correlated with insulin sensitivity in humans and impairs mitochondrial respiration in HepG2 cells

FRONTIERS IN PHYSIOLOGY, 2022, 13, 950791-950791 dx.doi.org/10.3389/fphys.2022.950791

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