AINA LLUCH BALAÑA

Projectes

Nutrició, Eumetabolisme i Salut

Papel de la Olfactomedina 2 (OLFM2) en el tejido adiposo en relación con la obesidad

Codi oficial: PI18/00550 Data inici: 01/01/2019 Data fi: 31/12/2022 Investigador/a principal: FRANCISCO JOSÉ ORTEGA DELGADO Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 111,320 €

Nutrició, Eumetabolisme i Salut

Ayuda de personal PFIS

Codi oficial: FI19/00045 Data inici: 01/01/2020 Data fi: 31/12/2023 Investigador/a principal: FRANCISCO JOSÉ ORTEGA DELGADO Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 82,400 €

Nutrició, Eumetabolisme i Salut

Señalización Auto-paracrina de la gamma-Sinucleína Derivada del Tejido Adiposo en Patología Relacionada con la Obesidad

Codi oficial: PI21/00074 Data inici: 01/01/2022 Data fi: 31/12/2024 Investigador/a principal: FRANCISCO JOSÉ ORTEGA DELGADO Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 145,200 €

Publicacions

Nutrició, Eumetabolisme i Salut

Rodríguez-Barrueco R, Latorre J, Devis-Jáuregui L, Lluch A, Bonifaci N, Llobet FJ, Olivan M, Coll-Iglesias L, Gassner K, Davis ML, Moreno-Navarrete JM, Castells-Nobau A, Plata-Peña L, Dalmau-Pastor M, Höring M, Liebisch G, Olkkonen VM, Arnoriaga-Rodríguez M, Ricart W, Fernández-Real JM, Silva JM, Ortega FJ, Llobet-Navas D

A microRNA Cluster Controls Fat Cell Differentiation and Adipose Tissue Expansion By Regulating SNCG.

Advanced Science, 2022, 9 dx.doi.org/10.1002/advs.202104759

Nutrició, Eumetabolisme i Salut

Latorre J, Ortega F, Oliveras-Cañellas N, Comas F, Lluch A, Gavaldà-Navarro A, Morón-Ros S, Ricart W, Villarroya F, Giralt M, Fernández-Real JM, Moreno-Navarrete JM

Specific adipose tissue Lbp gene knockdown prevents diet-induced body weight gain, impacting fat accretion-related gene and protein expression.

MOL THER-NUCL ACIDS, 2022, 27, 870-879 dx.doi.org/10.1016/j.omtn.2022.01.002

Nutrició, Eumetabolisme i Salut

Moreno-Navarrete JM, Latorre J, Lluch A, Ortega FJ, Comas F, Arnoriaga-Rodríguez M, Ricart W, Fernández-Real JM

Lysozyme is a component of the innate immune system linked to obesity associated-chronic low-grade inflammation and altered glucose tolerance.

CLINICAL NUTRITION, 2021, 40, 1420-1429 dx.doi.org/10.1016/j.clnu.2020.08.036

Nutrició, Eumetabolisme i Salut

Comas F, Latorre J, Ortega F, Oliveras-Cañellas N, Lluch A, Ricart W, Fernández-Real JM, Moreno-Navarrete JM

Permanent cystathionine-ß-Synthase gene knockdown promotes inflammation and oxidative stress in immortalized human adipose-derived mesenchymal stem cells, enhancing their adipogenic capacity.

Redox Biology, 2021, 42, 101668-101668 dx.doi.org/10.1016/j.redox.2020.101668

Nutrició, Eumetabolisme i Salut

Comas F, Latorre J, Ortega F, Arnoriaga Rodríguez M, Lluch A, Sabater M, Rius F, Ribas X, Costas M, Ricart W, Lecube A, Fernández-Real JM, Moreno-Navarrete JM

Morbidly obese subjects show increased serum sulfide in proportion to fat mass.

INTERNATIONAL JOURNAL OF OBESITY, 2021, 45, 415-426 dx.doi.org/10.1038/s41366-020-00696-z

Nutrició, Eumetabolisme i Salut

Comas F, Latorre J, Ortega F, Arnoriaga Rodríguez M, Kern M, Lluch A, Ricart W, Blüher M, Gotor C, Romero LC, Fernández-Real JM, Moreno-Navarrete JM

Activation of Endogenous H 2 S Biosynthesis or Supplementation with Exogenous H 2 S Enhances Adipose Tissue Adipogenesis and Preserves Adipocyte Physiology in Humans.

ANTIOXIDANTS & REDOX SIGNALING, 2021, 35, 319-340 dx.doi.org/10.1089/ars.2020.8206

Nutrició, Eumetabolisme i Salut

Latorre J, Lluch A, Ortega FJ, Gavaldà-Navarro A, Comas F, Morón-Ros S, Rodríguez A, Becerril S, Villarroya F, Frühbeck G, Ricart W, Giralt M, Fernández-Real JM, Moreno-Navarrete JM

Adipose tissue knockdown of lysozyme reduces local inflammation and improves adipogenesis in high-fat diet-fed mice.

PHARMACOLOGICAL RESEARCH, 2021, 166, 105486-105486 dx.doi.org/10.1016/j.phrs.2021.105486

Nutrició, Eumetabolisme i Salut

Santamaria-Martos F, Benitez ID, Latorre J, Lluch A, Moreno-Navarrete JM, Sabater M, Ricart W, Sanchez de la Torre M, Mora S, Fernández-Real JM, Ortega FJ

Comparative and functional analysis of plasma membrane-derived extracellular vesicles from obese vs. nonobese women.

CLINICAL NUTRITION, 2020, 39, 1067-1076 dx.doi.org/10.1016/j.clnu.2019.04.008

Nutrició, Eumetabolisme i Salut

Latorre J, Ortega FJ, Liñares-Pose L, Moreno-Navarrete JM, Lluch A, Comas F, Oliveras-Cañellas N, Ricart W, Höring M, Zhou Y, Liebisch G, Nidhina Haridas PA, Olkkonen VM, López M, Fernández-Real JM

Compounds that modulate AMPK activity and hepatic steatosis impact the biosynthesis of microRNAs required to maintain lipid homeostasis in hepatocytes.

EBioMedicine, 2020, 53, 102697-102697 dx.doi.org/10.1016/j.ebiom.2020.102697

Cirurgia General i Digestiva , Nutrició, Eumetabolisme i Salut

Ortega FJ, Moreno-Navarrete JM, Mercader JM, Gómez-Serrano M, García-Santos E, Latorre J, Lluch A, Sabater M, Caballano-Infantes E, Guzmán R, Macías-González M, Buxo M, Gironés J, Vilallonga R, Naon D, Botas P, Delgado E, Corella D, Burcelin R, Frühbeck G, Ricart W, Simó R, Castrillon-Rodríguez I, Tinahones FJ, Bosch F, Vidal-Puig A, Malagón MM, Peral B, Zorzano A, Fernández-Real JM

Cytoskeletal transgelin 2 contributes to gender-dependent adipose tissue expandability and immune function.

FASEB JOURNAL, 2019, 33, 9656-9671 dx.doi.org/10.1096/fj.201900479R

Directori

Projectes

Publicacions

A microRNA Cluster Controls Fat Cell Differentiation and Adipose Tissue Expansion By Regulating SNCG.

Specific adipose tissue Lbp gene knockdown prevents diet-induced body weight gain, impacting fat accretion-related gene and protein expression.

Lysozyme is a component of the innate immune system linked to obesity associated-chronic low-grade inflammation and altered glucose tolerance.

Permanent cystathionine-ß-Synthase gene knockdown promotes inflammation and oxidative stress in immortalized human adipose-derived mesenchymal stem cells, enhancing their adipogenic capacity.

Morbidly obese subjects show increased serum sulfide in proportion to fat mass.

Activation of Endogenous H 2 S Biosynthesis or Supplementation with Exogenous H 2 S Enhances Adipose Tissue Adipogenesis and Preserves Adipocyte Physiology in Humans.

Adipose tissue knockdown of lysozyme reduces local inflammation and improves adipogenesis in high-fat diet-fed mice.

Comparative and functional analysis of plasma membrane-derived extracellular vesicles from obese vs. nonobese women.

Compounds that modulate AMPK activity and hepatic steatosis impact the biosynthesis of microRNAs required to maintain lipid homeostasis in hepatocytes.

Cytoskeletal transgelin 2 contributes to gender-dependent adipose tissue expandability and immune function.

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