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The Metabolic and Maternofoetal research group is a multidisciplinary research group (basic researchers, clinicians, paediatricians and gynaecologists) that studies different metabolic and (epi)genetic markers associated with maternal and new-born metabolism for early identification of paediatric population at risk of developing metabolic diseases and obesity.

Main lines of research

Identification of metabolic and (epi)genetic markers associated with metabolic alterations in pregnancy and new-borns, and their relationship to pre- and post-natal growth.

Strategic objectives

The metabolic research group is characterized by extensive experience in both clinical and applied basic research, endorsed by competitive and overlapping funding from national and European research projects, as well as by publications in international journals in the field of the first quartile and decile in the line of energy metabolism from gestation to the paediatric age.

The group’s strategic objectives are below:

  • Cardiometabolic risk markers in the paediatric age
  • Metabolic programming during pregnancy
  • Epigenetics of development: miRNA and DNA methylation
  • Pathophysiological bases of low birth weight
  • Pharmacological reversibility of metabolic programming
  • New technologies applied to maternal and child health
Publications

Maroto A, Martinez-Diago C, Tio G, Sagues M, Borrell A, Bonmati A, Teixidor M, Adrados C, Torrent S, Alvarez E

Autoimmune hemolytic anemia in pregnancy: a challenge for maternal and fetal follow-up.

JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE, 2022, 35, 1-3 dx.doi.org/10.1080/14767058.2020.1732344

Carreras-Badosa G, Gómez-Vilarrubla A, Mas-Parés B, Martínez-Calcerrada JM, Xargay-Torrent S, Prats-Puig A, Puerto-Carranza E, Díaz-Roldán F, de Zegher F, Ibañez L, Bassols J, López-Bermejo A

A 24-month metformin treatment study of children with obesity: Changes in circulating GDF-15 and associations with changes in body weight and visceral fat.

Pediatric Obesity, 2022, 17 dx.doi.org/10.1111/ijpo.12845
0

TSH and FT4 reference intervals in pregnancy: a systematic review and individual participant data meta-analysis.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2022, 107, 2925-2933 dx.doi.org/10.1210/clinem/dgac425
0

microRNAs in newborns with low birth weight: relation to birth size and body composition.

PEDIATRIC RESEARCH, 2022, 92, 829-837 dx.doi.org/10.1038/s41390-021-01845-4
0

Association of thyroid peroxidase antibodies and thyroglobulin antibodies with thyroid function in pregnancy - an individual participant data meta-analysis.

Thyroid, 2022, 32, 828-840 dx.doi.org/10.1089/thy.2022.0083
0

Metabolic programming in the offspring after gestational overfeeding in the mother: toward neonatal rescuing with metformin in a swine model.

INTERNATIONAL JOURNAL OF OBESITY, 2022, 46, 1018-1026 dx.doi.org/10.1038/s41366-022-01076-5
0

Association between maternal thyroid function and risk of gestational hypertension and pre-eclampsia: a systematic review and individual-participant data meta-analysis.

LANCET DIABETES & ENDOCRINOLOGY, 2022, 10, 243-252 dx.doi.org/10.1016/S2213-8587(22)00007-9
0

Catch-up growth in juvenile rats, fat expansion, and dysregulation of visceral adipose tissue.

PEDIATRIC RESEARCH, 2022, 91, 107-115 dx.doi.org/10.1038/s41390-021-01422-9

Garre-Olmo J, Turró-Garriga O, Martí-Lluch R, Zacarías-Pons L, Alves-Cabratosa L, Serrano-Sarbosa D, Vilalta-Franch J, Ramos R

Changes in lifestyle resulting from confinement due to COVID-19 and depressive symptomatology: A cross-sectional a population-based study.

COMPREHENSIVE PSYCHIATRY, 2021, 104, 152214-152214 dx.doi.org/10.1016/j.comppsych.2020.152214

Xargay-Torrent S, Puerto-Carranza E, Marcelo I, Mas-Parés B, Gómez-Vilarrubla A, Martínez-Calcerrada JM, de Zegher F, Ibáñez L, López-Bermejo A, Bassols J

Estimated glomerular filtration rate and cardiometabolic risk factors in a longitudinal cohort of children.

SCIENTIFIC REPORTS, 2021, 11, 11702-11702 dx.doi.org/10.1038/s41598-021-91162-x
Competitive projects
Codi oficial: PI19/00451 Start date:01/01/2020 Data fi: 31/12/2023 Investigador/a principal: JUDIT BASSOLS CASADEVALL Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 101,640 €
Codi oficial: PI20/00399 Start date:01/01/2021 Data fi: 31/12/2023 Investigador/a principal: JUDIT BASSOLS CASADEVALL Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 93,170 €
Codi oficial: 210653186 Start date:01/04/2021 Data fi: 31/03/2026 Investigador/a principal: JUDIT BASSOLS CASADEVALL Organisme finançador: EUROPEAN COMISSION Ajuda: 231,535 €
Codi oficial: FI18/00144 Start date:01/01/2019 Data fi: 31/05/2023 Investigador/a principal: JUDIT BASSOLS CASADEVALL Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 82,400 €
Codi oficial: IA, epigenetica y predicción de la obesidad infantil Start date:01/06/2022 Data fi: 31/05/2023 Investigador/a principal: JUDIT BASSOLS CASADEVALL Organisme finançador: FUND. SOC.ESP.ENDOCRINOLOGIA PEDIATR Ajuda: 7,000 €
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