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The Metabolic and Maternofoetal research group is a multidisciplinary research group (basic researchers, clinicians, paediatricians and gynaecologists) that studies different metabolic and (epi)genetic markers associated with maternal and new-born metabolism for early identification of paediatric population at risk of developing metabolic diseases and obesity.

Main lines of research

Identification of metabolic and (epi)genetic markers associated with metabolic alterations in pregnancy and new-borns, and their relationship to pre- and post-natal growth.

Strategic objectives

The metabolic research group is characterized by extensive experience in both clinical and applied basic research, endorsed by competitive and overlapping funding from national and European research projects, as well as by publications in international journals in the field of the first quartile and decile in the line of energy metabolism from gestation to the paediatric age.

The group’s strategic objectives are below:

  • Cardiometabolic risk markers in the paediatric age
  • Metabolic programming during pregnancy
  • Epigenetics of development: miRNA and DNA methylation
  • Pathophysiological bases of low birth weight
  • Pharmacological reversibility of metabolic programming
  • New technologies applied to maternal and child health
Publications

Garre-Olmo J, Turró-Garriga O, Martí-Lluch R, Zacarías-Pons L, Alves-Cabratosa L, Serrano-Sarbosa D, Vilalta-Franch J, Ramos R, Girona Healthy Region Study Group

Changes in lifestyle resulting from confinement due to COVID-19 and depressive symptomatology: A cross-sectional a population-based study.

COMPREHENSIVE PSYCHIATRY, 2021, 104, 152214-152214 dx.doi.org/10.1016/j.comppsych.2020.152214

Xargay-Torrent S, Puerto-Carranza E, Marcelo I, Mas-Parés B, Gómez-Vilarrubla A, Martínez-Calcerrada JM, de Zegher F, Ibáñez L, López-Bermejo A, Bassols J

Estimated glomerular filtration rate and cardiometabolic risk factors in a longitudinal cohort of children.

SCIENTIFIC REPORTS, 2021, 11, 11702-11702 dx.doi.org/10.1038/s41598-021-91162-x

Bassols J, Martínez-Calcerrada JM, Osiniri I, Díaz-Roldán F, Xargay-Torrent S, Mas-Parés B, Dorado-Ceballos E, Prats-Puig A, Carreras-Badosa G, de Zegher F, Ibáñez L, López-Bermejo A

Effects of metformin administration on endocrine-metabolic parameters, visceral adiposity and cardiovascular risk factors in children with obesity and risk markers for metabolic syndrome: A pilot study.

Plos One, 2019, 14, e0226303 dx.doi.org/10.1371/journal.pone.0226303

Mas-Parés B, Xargay-Torrent S, Bonmatí A, Lizarraga-Mollinedo E, Martínez-Calcerrada JM, Carreras-Badosa G, Prats-Puig A, de Zegher F, Ibáñez L, López-Bermejo A, Bassols J

Umbilical Cord miRNAs in Small-for-Gestational-Age Children and Association With Catch-Up Growth: A Pilot Study.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2019, 104, 5285-5298 dx.doi.org/10.1210/jc.2018-02346

Bassols J, Martínez-Calcerrada JM, Prats-Puig A, Carreras-Badosa G, Xargay-Torrent S, Lizarraga-Mollinedo E, Feliu-Alsina M, Riera-Pérez E, Osiniri I, de Zegher F, Ibáñez L, López-Bermejo A

Perirenal fat is related to carotid intima-media thickness in children.

INTERNATIONAL JOURNAL OF OBESITY, 2018, 42, 641-647 dx.doi.org/10.1038/ijo.2017.236

Carreras-Badosa G, Bonmatí A, Ortega FJ, Mercader JM, Guindo-Martínez M, Torrents D, Prats-Puig A, Martinez-Calcerrada JM, de Zegher F, Ibáñez L, Fernandez-Real JM, Lopez-Bermejo A, Bassols J

Dysregulation of Placental miRNA in Maternal Obesity Is Associated With Pre- and Postnatal Growth.

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2017, 102, 2584-2594 dx.doi.org/10.1210/jc.2017-00089

Prats-Puig A, Moreno M, Carreras-Badosa G, Bassols J, Ricart W, López-Bermejo A, Fernández-Real JM

Serum Ferritin Relates to Carotid Intima-Media Thickness in Offspring of Fathers With Higher Serum Ferritin Levels.

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2016, 36, 174-180 dx.doi.org/10.1161/ATVBAHA.115.306396

Bassols J, Moreno-Navarrete J, Carreras-Badosa G, Diaz M, Prats-Puig A, Palomer AM, de Zegher F, Ibáñez L, Fernandez-Real JM, Lopez-Bermejo A

Placental sprouty 2 (SPRY2): relation to placental growth and maternal metabolic status.

Neonatology, 2014, 106, 120-125 dx.doi.org/10.1159/000362783

Ortega FJ, Vazquez-Martin A, Moreno-Navarrete JM, Bassols J, Rodriguez-Hermosa J, Gironés J, Ricart W, Peral B, Tinahones FJ, Fruhbeck G, Menendez JA, Fernández-Real JM

Thyroid hormone responsive Spot 14 increases during differentiation of human adipocytes and its expression is down-regulated in obese subjects.

INTERNATIONAL JOURNAL OF OBESITY, 2010, 34, 487-499 dx.doi.org/10.1038/ijo.2009.263

Bassols J, Botas P, Moreno-Navarrete JM, Delgado E, Ortega F, Ricart W, Fernandez-Real JM

Environmental and Genetic Factors Influence the Relationship Between Circulating IL-10 and Obesity Phenotypes

Obesity, 2010, 18, 611-618 dx.doi.org/10.1038/oby.2009.313
Competitive projects
Codi oficial: PI19/00451 Start date:01/01/2020 Data fi: 31/12/2022 Investigador/a principal: JUDIT BASSOLS CASADEVALL Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 101,640 €
Codi oficial: PI20/00399 Start date:01/01/2021 Data fi: 31/12/2023 Investigador/a principal: JUDIT BASSOLS CASADEVALL Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 93,170 €
Codi oficial: 210653186 Start date:01/04/2021 Data fi: 31/03/2026 Investigador/a principal: JUDIT BASSOLS CASADEVALL Organisme finançador: EUROPEAN COMISSION Ajuda: 231,535 €
Codi oficial: FI18/00144 Start date:01/01/2019 Data fi: 31/12/2022 Investigador/a principal: JUDIT BASSOLS CASADEVALL Organisme finançador: INSTITUTO DE SALUD CARLOS III Ajuda: 82,400 €
Codi oficial: SCE 2017 Start date:21/03/2017 Data fi: 31/12/2021 Investigador/a principal: JUDIT BASSOLS CASADEVALL Organisme finançador: FUNDACIÓ ACADÈMIA CIÈNCIES MÈDIQUES Ajuda: 9,000 €
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