Epidemiology, clinical features, and prognosis of elderly adults with severe forms of influenza A (H1N1.

Epidemiology, clinical features, and prognosis of elderly adults with severe forms of influenza A (H1N1.

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OBJECTIVES: To examine epidemiological and clinical data of individuals aged 65 and older with influenza virus A (H1N1) admitted to the intensive care unit (ICU) and to identify independent predictors of ICU mortality. DESIGN: Prospective, observational, multicenter study to determine prognostic factors in individuals infected with influenza A (H1N1) admitted to the ICU. SETTING: One hundred forty-eight Spanish ICUs. PARTICIPANTS: Individuals with influenza A (H1N1) confirmed using real-time polymerase chain reaction from April 2009 to July 2011. MEASUREMENTS: Individuals aged 65 and older were compared with younger individuals. A multivariate analysis was conducted to determine independent predictors of mortality in this population. RESULTS: One thousand one hundred twenty individuals (129 (11.5%) aged 65) were included. Prevalence of chronic diseases was more common in older individuals. Viral pneumonitis was more frequent in individuals younger than 65 (70.5% vs 54.3%, P

Media title: 
Journal of the American Geriatrics Society
Quartile: 
1