Lluís Ramió i Torrentà

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VIII Jornades Gironines del Mediterrani en Esclerosi Múltiple- 2018

VIII Jornades Gironines del Mediterrani en Esclerosi Múltiple- 2018

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Jornades Gironines del Mediterrani en Esclerosi Múltiple

Jornades Gironines del Mediterrani en Esclerosi Múltiple

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Similar biological effect of high-dose oral versus intravenous methylprednisolone in multiple sclerosis relapses

Similar biological effect of high-dose oral versus intravenous methylprednisolone in multiple sclerosis relapses

Our aim was to investigate differences in immune mechanisms in multiple sclerosis (MS) relapse, after high-dose oral methylprednisolone (oMP) or intravenous methylprednisolone (ivMP). We measured serum cytokines (IL-2, IL-4, IL-6, IL-10, IL-17, TNF-α and IFN-γ) in 39 of 49 MS patients with moderate-severe relapse, whom were treated with ivMP or oMP in a placebo-controlled, non-inferiority clinical trial. We assessed these cytokine levels at baseline and at 1 and 4 weeks post-treatment.

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